A tall, slender vase stands at the center of the composition, filled with a profusion of flowers that spill outward in all directions. The bouquet includes blossoms in vivid reds, deep blues, pale pinks, and creamy whites, each rendered with distinct, expressive brushwork that gives the petals a sense of movement and delicacy. Stems and leaves arc and twist, some painted in sharp detail, others dissolving into the softly textured background, which shifts in tone from warm beige to cooler gray.

Butterflies and moths hover around the bouquet, their wings captured in mid-flight with strokes of blue, yellow, and white, adding a sense of life and transience to the still life. A pair of blue butterflies appear near the lower right, while a white butterfly with patterned wings floats in the upper right, and other insects are scattered delicately across the upper half of the canvas. The background is loosely painted, with visible brushstrokes and areas where the canvas texture shows through, creating a luminous, atmospheric effect that sets off the vivid colors of the flowers and insects.

The composition is asymmetrical, with the bouquet leaning slightly to the left and the tallest stems and petals reaching toward the upper edge of the canvas, giving the arrangement a sense of upward movement. Small details, such as the curling tips of leaves and the fine dots of pollen or seeds, are picked out with quick, precise touches of the brush. The artist’s signature, 'ODILON REDON,' appears in the lower right corner, anchoring the work with his name. Still Life with Flowers was created by Odilon Redon in 1905.

The Art Institute of Chicago lists the work as a gift from Mary and Leigh Block and displays it in Gallery 245. The museum’s record confirms the subject as a bouquet of flowers, emphasizing the central role of floral forms in the composition.