In Portrait of a Man, the subject is depicted with a serious expression, dressed in dark clothing. The background is a subtle, muted color that enhances the focus on the figure. The use of light and shadow creates depth and realism in the portrayal.

Rich, earthy tones dominate the palette, contributing to the overall somber mood. The painting is executed in oil on panel, a common medium during the Northern Renaissance. Antonello da Messina's technique is characterized by meticulous detail and a smooth finish. The careful rendering of textures, especially in the fabric and skin, showcases his skill.

The dimensions are approximately 60 x 80 cm, making it a relatively intimate portrait. Antonello da Messina was a pivotal figure in the Northern Renaissance, known for his innovative use of oil paint. Portrait of a Man is notable for its psychological depth and realism, which were groundbreaking for its time. An interesting fact about this work is that it reflects the artist's interest in human emotion and individuality.

This painting is part of the collection at the Museo Thyssen-Bornemisza in Spain.