In Filles aux grands sables, two women stand in a sandy landscape, surrounded by a vibrant array of colors. The painting features bold brushstrokes that create a sense of movement and life. The figures are depicted in a stylized manner, emphasizing their forms against the backdrop of the sandy terrain.

The overall composition exudes a playful yet serene atmosphere. The painting is executed in oil on canvas, a medium that allows for rich color layering and texture. Sérusier employs a palette dominated by warm yellows, soft oranges, and earthy browns, which harmonize beautifully. The brushwork is loose and expressive, characteristic of the Post-Impressionism style.

This technique invites viewers to engage with the painting on a sensory level. Paul Sérusier was a key figure in the Post-Impressionism movement and a member of the Nabis group, known for their innovative use of color and form. Filles aux grands sables reflects Sérusier's interest in capturing the essence of his subjects rather than their realistic details. An interesting fact about this work is that it embodies the principles of color theory that Sérusier and his contemporaries explored.

This painting is a testament to the evolution of modern art in the late 19th century.