In Self Portrait, Sofonisba Anguissola presents herself with a thoughtful expression. The colors are warm, with soft browns and gentle highlights that illuminate her face. She wears a dark dress adorned with a delicate collar, which contrasts with her fair skin.

The background is subtle, allowing the viewer to focus on her features and demeanor. This painting is executed in oil on panel, a common medium during the Renaissance. Anguissola's technique showcases her skill in capturing light and texture, particularly in the rendering of her skin and fabric. The composition is intimate, inviting viewers to connect with the artist personally.

The dimensions are approximately 60 x 80 cm, making it a modest yet impactful work. Sofonisba Anguissola was a pioneering female artist in the Renaissance, known for her portraits that often included family members. This self-portrait is significant as it reflects her individuality and confidence as an artist. Interestingly, Anguissola was one of the first women to gain recognition in the male-dominated art world of her time.

Her works influenced later generations of artists, including Diego Velázquez.