Two monumental male figures stand side by side at the center, each holding a distinct attribute in their right hand: the left figure presents a large key, while the right figure raises a sword upright. Both men are barefoot and draped in voluminous robes that swirl around their bodies, with the folds rendered in soft, rounded forms that suggest a heavy, supple fabric. The left figure, with long, curly hair and a full beard, gazes outward with a calm, steady expression, his left hand resting gently on the other man's wrist.

The right figure, older and with tightly curled white hair and beard, looks slightly upward and outward, his brows furrowed in a look of intensity or contemplation. A winged cherub hovers above the two men, clutching a papal tiara and a pair of crossed keys, while another cherub peeks from behind the left figure's leg, holding a book. A dove, its wings spread, glides in the upper background, adding a sense of movement and suggesting a spiritual presence.

The figures are set against a shallow architectural backdrop, with a column visible on the far left and a pilaster on the right, framing the scene and giving it a sense of grandeur. Light falls from the upper left, illuminating the faces and drapery, and casting deep shadows that model the forms with dramatic contrast. Brushwork appears smooth and controlled, with soft transitions in the flesh and fabric, and sharper lines used to define the edges of the sword, key, and architectural elements.

The composition is tightly organized, with the two saints forming a powerful vertical axis at the center, while the diagonals of their arms and the sword create a dynamic rhythm. Small details, such as the delicate feathers of the dove and cherubs, the veins on the saints’ hands, and the intricate decoration of the papal tiara, are rendered with precision and care.