A woman in a vivid red dress sits at the center, cradling a fair-haired infant who reaches up to touch her chin. Her gaze is gentle and affectionate, and her right arm supports the child’s back while her left hand steadies his legs. To her left, a bearded man in a blue cloak leans in, his face close to the child, watching the interaction with a tender expression.

In front of the woman, another small child, dressed in a simple cloth, stands with his back to the viewer and stretches up toward the infant, one hand resting on the woman’s knee. A lamb stands beside this child, its white fleece contrasting with the warm tones of the figures, and its head turned toward the group. On the right, an older woman in a dark dress and white headdress observes the scene with a look of quiet satisfaction, her hands resting on her knees as she leans forward.

A large woven basket with folded linens sits in the lower right corner, its texture rendered with careful brushwork, while the wooden floorboards beneath the figures are painted in broad, smooth strokes. Light streams in from the left, illuminating the faces and bodies of the figures and casting subtle shadows that model their forms. The palette is rich and saturated, dominated by the red of the woman’s dress, the blue of her sleeve, and the creamy flesh tones, all set off by the darker background and the soft white of the lamb and basket linens.

The brushwork is fluid and confident, with smooth transitions in the flesh and drapery, and more textured strokes in the background and basket. The composition draws the figures together in a close, intimate grouping, their gestures and glances forming a circle of affection and attention. The title The Holy Family with Saint Elizabeth and Saint John the Baptist appears in the museum's documentation for this composition.