In Virgin Mary with child and a saint or donor, we see the Virgin Mary holding the infant Jesus, surrounded by a saint or a donor figure. The colors are rich and vibrant, typical of Anthony van Dyck's Baroque style. The figures are depicted with great attention to detail, showcasing their expressions and garments.

The setting is likely a religious context, enhancing the spiritual atmosphere of the painting. The painting is executed in oil on canvas, a common medium for Baroque artists. Van Dyck's technique includes smooth brushwork and a careful layering of colors to create depth. The composition is balanced, with the figures arranged in a way that draws the viewer's eye towards the central figures of Mary and Jesus.

The use of light and shadow adds a three-dimensional quality to the work. Anthony van Dyck was a prominent Flemish painter known for his portraits and religious works. This painting reflects his ability to convey emotion and spirituality through his subjects. An interesting fact about this work is that it showcases Van Dyck's transition from the influence of Rubens to his own distinctive style, which would later influence many artists in Europe.

The work is housed in the Museo del Prado, one of the most important art museums in Spain.