In William Henry Vanderbilt, Eastman Johnson presents a formal portrait of the wealthy industrialist. The painting features a well-dressed Vanderbilt, exuding confidence and authority. The color palette is rich, with deep blues and warm browns dominating the composition.

The background is subtly blurred, drawing attention to Vanderbilt's figure and expression. This artwork is created using oil on canvas, a common medium for portraiture in the 19th century. The dimensions are approximately 76 x 102 cm, making it a substantial piece that commands attention. Johnson's brushwork is detailed, particularly in the rendering of Vanderbilt's clothing and facial features.

The realistic style captures the subject's character and status. Eastman Johnson, an American painter, was known for his portraits of prominent figures in society. This particular work reflects the wealth and influence of Vanderbilt, a key figure in the American railroad industry. Interestingly, Johnson was also a member of the Hudson River School, which is known for its landscapes, yet he excelled in portraiture as well.

The painting serves as a testament to both Vanderbilt's legacy and Johnson's skill.